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Chromatography in Biologics Manufacturing: Purification Science, Resin Applications, and System Qualification

Chromatography in Biologics Manufacturing: Science, Purpose, and Resin Applications  Chromatography is a critical purification technique used in many evolving fields of biologics manufacturing including monoclonal...

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From Day One Success to Everyday Improvement: The OR → OE Continuum 

Written by Paige Kane, PhD, CPIP   If you work in Life Sciences, you know that it is a complex, high-stakes operation.  I’ve been through my...

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WINDSOR FRAMEWORK: WHAT IS IT?

The Windsor Framework (WF), which came into effect on January 1, 2025, is a significant agreement between the UK and the EU that replaces the...

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Balancing Scalability, Speed, and Quality in Pharma Startups 

Pharmaceutical companies today face a high-stakes equation: launch faster, meet global demand, and maintain quality and compliance—without fail. That means simultaneously spinning up manufacturing sites,...

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Navigating Regulatory Complexity in Life Sciences: Turning Compliance into a Strategic Advantage 

As global regulations continue to evolve, life sciences companies are facing increasing pressure to meet stringent compliance requirements without slowing down innovation or compromising product...

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Engaging Early: FDA’s Collaborative Pathways for AI in Regulatory Applications (Part 3 of 3)

Nick Armstrong, Senior Director of Digital Enablement at CAI and co-chair of the ISPE Community of Practice on AI, specializes in the intersection of artificial...

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A Framework for Trust: Understanding the FDA’s AI Risk-Based Credibility Assessment (Part 1 of 3) 

Nick Armstrong, Senior Director of Digital Enablement at CAI and co-chair of the ISPE Community of Practice on AI, specializes in the intersection of artificial...

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Innovative Approaches to Quality and Engineering Management: Transforming Life Sciences Manufacturing

The path to operational excellence is continually being redefined. Today’s manufacturers face mounting pressure to enhance product quality, improve compliance, and optimize operational efficiency—all while...

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The Future of AI-Driven Operational Readiness – An Outcome-Based Approach to Enhanced Process Validation and Asset Performance

As AI and related technologies continue to advance, the potential to reshape operational readiness grows exponentially. The future of AI for use in operational readiness...

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